Allergy, Asthma, Immunology of Delaware
Nasheds, PA          Maher Nashed MD



Stress and Allergy Flare up

 The findings suggest that individuals with persistent emotional stress have more frequent allergy flares. Furthermore, those with more flares have greater negative mood.  
Amber Patterson. et,al. Received 9 May 2013; received in revised form 3 July 2013; accepted 11 July 2013.  published online 08 August 2013.

Pet Allergy

Pet removal is an effective way to decrease exposure to allergen.
Patients who removed the pet had decreased airway hyperresponsiveness and decreased use of asthma controller medication after 1 year.
Even after pet removal, residual allergen can persist.
Further, dog and cat allergens are found in homes without pets.

​Allergy and Mold exposure

The risk of having nose allergy is high if you get exposed to dampness and molds at home. The relationship is higher if there is molds odor in the house. JACI v132. Nov 2013
Approximately 5% to 20% of individuals with atopy/allergy are sensitized to mold.
Mold depends on moisture for growth, and individual molds thrive on different levels of moisture to support growth.
Common indoor molds include Fusarium, Penicillium, and Aspergillus species; some molds require higher moisture including Penicillium, Aspergillus, Stachybotrys, and Chaetomium species, so these molds can be found indoors in the setting of sustained water intrusion.
Common outdoor molds include Cladosporium, Alternaria, and Epicoccum species. , Alternaria and Cladosporium species grow outdoors in a damp or humid environment.
Many outdoor molds contaminate indoor areas by way of open windows, clothing, or pet fur.

Mold Allergy

Dog Allergy

Sebaceous glands secrete dog allergen which is found in canine saliva, fur, and dander.
Reservoirs for dog allergen include bedding, furniture, and carpeting.

Hypo Allergenic Dogs

Many patients allergic to dog report better tolerance of certain breeds over others, leading to various breeds being referred to as hypoallergenic.
In a study that examined dust samples taken from homes with various breeds of dogs, those in homes with hypoallergenic breeds had no difference in Can f 1 (dog allergen) levels compared with other breeds.
Another study found that Can f 1 levels were actually higher in hair and coat samples in breeds that were touted as hypoallergenic. Currently, evidence does not support breed-specific differences in allergenicity.

Cat Allergy

Cat allergen; it is found primarily on skin and fur and is produced in sebaceous, anal, and salivary glands.
Highly concentrated areas of cat allergen include upholstery, bedding, and carpet.
After removal of cats from the home, the decrease of Fel d 1 (cat allergen) levels can be slow over time. Therefore, although removal of cat from the environment is important, other methods of allergen elimination are necessary.

Dust Allergy

Dust mites require adequate moisture and a feeding source for survival, so abatement tactics should focus on these factors.
Dust mites feed off dead skin cells and microorganisms, so minimizing the food source as a facilitating factor can decrease dust mites in the environment.
Dust mites thrive in humid environments, so maintaining humidity below 50% limits dust mite growth.
The common household dust mites in the United States are Dermatophagoides farinae and Dermatophagoides pteronyssinus, and the major allergenic proteins are Der p 1 and Der f 1.

Roaches Allergy

A major allergen in cockroach is found in cockroach fecal material.
Asthma morbidity in inner-city children is associated with cockroach allergy.
Further, cockroach exposure in inner-city children has been indicated as a risk factor in the development of asthma

Rodents Allergy

The primary source of allergen from pests such as mice and rats is urine,
Mouse allergen is prevalent in inner-city and suburban home and schools,
Whereas rat allergen is less prevalent than mouse but still common in the inner-city setting.
Individuals sensitized and exposed to rodents in turn can have higher asthma morbidity, highlighting the importance of abatement tactics in homes and schools.

​Is it cold or allergy. 
Both can have similar symptoms but there are main differences
If you have a cold
1. You get fever, generalized aches and pain. These don’t happen with allergy
2. Sore painful throat usually comes with the colds.
3. They often take several days to show up after exposure to a virus/cold.
4. Colds tend to occur in the winter.
5. The symptoms of a cold typically last three to 14 days.
6. The nasal discharge might have a color.
If it is allergy 
1. You get itchy eyes.
2. They are seasonal.
3. Symptoms occur immediately after exposure to pollens in spring, summer or fall.
4. Allergy symptoms last longer, usually for weeks.
5. The nasal secretion is usually clear.
Common symptoms between both
1. Sneezing
2. Runny nose
3. Stuffy nose
4. Cough , but it is more common with colds
5. Fatigue and weakness (Sometimes)    

Cold or Allergy

Allergy and Migraine Headache

If you have nasal allergy (stuffy nose, runny nose or sneezing) for a long time, you might get more frequent and more severe Migraine headache than other people.
Chronic rhinitis and its association with headache frequency and disability in persons with migraine: Results of the American Migraine Prevalence and Prevention (AMPP) Study               
Allergic diseases and Cancer (Hodgkin Lymphoma)
The results of a study done may indicate true increased risk for Hodgkin Lymphoma with family history of autoimmune and allergic conditions that varies by tumor EBV status.
The study,
 Infectious, autoimmune, and allergic diseases and risk of Hodgkin lymphoma in children and adolescents: A Children-s Oncology Group (COG) study.
International Journal of CancerAccepted Articles, Accepted manuscript online: 13 FEB 2014

Allergy and Cancer

The type of washer and Dust numbers

 Hot-water washing reduced mean mite numbers by 78% (p5.03) in the top loader, and 90% (p5.01) in the front-loader. Cold-water washing reductions were 65% (p5.05) top-loader, but only 10% (p5.78) front-loader. Adding the non-bleach oxidizer to cold washes had no significant effect on surviving mite numbers in either machine.